Posted: 2023.12.5Updated: 2023.12.17

Intertwined climbing dendrites nestled against the soma of a neuron 

At least two to three times a year ever since I first left home for college, I have received an envelope stuffed to the gills from my mother in the mail containing newspaper clippings and articles covering all sorts of topics. Whenever I receive these envelopes, I usually will set them aside until the weekend, at which point I will usually make myself a drink, plop down on the couch, and diligently read each rticle, recycling each one as I go until the envelope is empty. Back in the early days at Michigan, most of the articles either focused on research involving wildlife or on how to eat something other than ramen noodles in college. 10 years and counting later, and I have just finished an article about how I should be eating more beans (thanks Mom), but the majority of articles are popular science articles about developments in neuroscience. This is great for me, because sometimes the big splashes in the field that bubble up into the public consciousness come from subdisciplines that I rarely interface with, so without her letterbombs I would have likely remained unaware of them. 


My most recent letter from her had some old articles that must have been misplaced somewhere and rediscovered, because this story was published back in 2021 from Science News (I couldn't find the link!). The story covers the release of this preprint from Jeff Lichtman's lab at Harvard, and describes a 1mm3 sample of cortical tissue from a 45-year-old woman (dubbed by the researchers H01) who had undergone surgery for epilepsy. What's cool about it is that they released all the data as a browsable web interface that anyone can check out. Here is a link to the main gallery where the authors have cherry picked some super cool features revealed by the EM stack, and lots of Unidentified Brain Objects (UBOs, if you will?) to boot! 

Blood vessel wrapping around the soma of a neuron.